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And when it becomes imbalanced due to everything from taking drugs like antibiotics and contraceptives, poor diet, like a diet high in sugar, low in fiber, emotional stress, this disrupts communication between your gut and your other organs, including your brain, and causes you to get sick

It's a signal that the population most likely to seek GLP-1 therapy for cosmetic and metabolic weight goals (rather than diabetes management) may be the population bearing the greatest skeletal cost

The same active ingredient is often sold under two brand names one for diabetes management and one for weight management

Eur J Pharmacol (2015) 755:95101