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"Sermorelin stimulates physiologic GH pulses, improving muscle recovery, connective tissue repair, and sleep quality critical elements of recovery and rehabilitation in both athletic and aging populations." Schmid et al., Neuroendocrinology Clinical Evidence Clinical studies have demonstrated that Sermorelin effectively increases GH and IGF-1, leading to improvements in lean body mass, sleep quality, and overall recovery capacity

GLP-1 receptor agonists like semaglutide and tirzepatide work through an entirely different mechanism: they activate incretin receptors in the pancreas and brain to reduce appetite, slow gastric emptying, and improve insulin sensitivity

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