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Microdosing GLP-1 drugs is gaining momentum on social media because people consume them to get some weight-loss or appetite-control benefits while avoiding strong side effects and reducing the high cost of treatment

Orforgliprion caused an average 11% weight loss among overweight and obese people after a year and a half, researchers reported in the New England Journal of Medicine

45 Identifying Optimal Candidates for GLP-1RA Therapy in Heart Failure The selection of patients with HF for GLP-1RA therapy requires careful consideration of the HF phenotype, comorbidities and available evidence

At the highest dose of 15mg, mean weight loss reached 20.9 percent over 72 weeks