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Some reports have indicated that altered FSH-signaling and/or over expression of FSHR can actually promote apoptosis in unselected follicles, which may potentially happen via excessive accumulation of cAMP or activation of p38 MAPK pathways (106, 135)
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Upon receptor engagement, BPC-157 initiates downstream phosphorylation cascades involving phospholipase C-gamma and protein kinase C activation, measurable through Western blot analysis and fluorescence-based kinase activity assays
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