SAM's many roles: SAM is the primary methyl donor, used in DNA/RNA methylation, protein modification, and synthesis of neurotransmitters and hormones
Fortunately, there is increasing evidence that oral B12 supplements are just as good as injections for raising blood levels in most people ( Vegetarians and vegans are usually advised to take at least 10 mcg per day, or at least 2,000 mcg once per week ( However, some doctors still prefer the use of injections
This is typical with any subcutaneous injection and usually resolves within an hour
On best use, NAD+ tends to suit systemic goals like low energy, fatigue, brain fog, and healthy aging support, whereas peptides suit targeted goals like skin quality, tissue repair, and recovery