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A recent meta-analysis of 11 randomized controlled trials demonstrated a 13-percent relative risk reduction for all-cause death, along with significant risk reductions across multiple outcomes, including 16 percent for renal failure, 13 percent for congestive heart failure hospitalizations, 14 percent for major adverse cardiovascular events, 12 percent for stroke, 13 percent for non-fatal myocardial infarction and 14 percent for cardiovascular death

They are not the same type of drug, they are not interchangeable, and combining them requires careful medical supervision with particular attention to cardiovascular monitoring

Many people find that taking these supplements with a small meal helps with absorption and prevents any potential stomach upset

There is limited information on the drugs long-term safety