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Overall, these findings indicate that the TGR inhibitors engage TGR in ex vivo worms
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27 OzakiH.HaradaS.TakeuchiT.KawaguchiS.TakahashiY.KojimaY.et al (2018)
Leptin is a hormone involved in regulating energy balance and appetite, which could imply that increased food intake may contribute to the observed weight gain in peptide-exposed models, which then may increase leptin levels and subdue appetite
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