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Combined use of NNMT gene knockout and the product confirms causality:NNMT inhibition enhanced NAD+ synthesis improved energy metabolism This provides a complete experimental evidence chain for NNMT's regulatory role
Thus, we can assume that pathways additional to those involved in angiogenesis (Vukojevic et al., 2018) are associated with the increased expression, internalization of VEGFR2, and the activation of the VEGFR2-Akt-eNOS signaling pathway (Hsieh et al., 2017)
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Wang XY, Qu M, Duan R, et al
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