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PMID: 195 GodetIM

Research shows that GLP-1 medications can extend active weight loss to around 24 months before plateauing, compared to roughly 12 months with calorie restriction alone, because they reduce compensatory hunger signals that normally halt progress

They were originally developed for type 2 diabetes and are now also used for weight management, for certain molecules and indications

Implications for insurers Insurers should consider the impact of AOMs across their business: Assess how AOMs may impact protection, morbidity, and longevity experience Review trend assumptions to identify whether changes are needed Establish processes to keep on top of this fast-moving space Consider new lapse risks Assess how AOMs might affect underwriting and claims Insured impacts and reviewing trend assumptions Insurers should consider adjustments to their specific mortality and morbidity improvement assumptions to reflect AOMs