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Table 11.6 Dietary Reference Intakes for Selenium Selenium at doses several thousand times the RDA can cause acute toxicity, and when ingested in gram quantities can be fatal

A sigma class glutathione S-transferase gene regulated by the CncC pathway is required for phytochemical tolerance in the red flour beetle, Tribolium castaneum

Since, without integrating PK/PD principles, clinical outcomes alone are insufficient to validate or refute the therapeutic potential of antioxidant strategies in AMS induced by hypobaric hypoxia conditions

However, this is very important: enthusiastic anecdotal reports are not a substitute for controlled clinical trials