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Le Prell et al., Reduction of the Cochlear Blood Flow and Vasodilators Exposure to loud noise, in addition to inducing oxidative stress, also diminishes cochlear blood flow by reducing blood vessel diameter and erythrocyte velocity in the basilar membrane, the spiral ligament and the SV (Sendowski, 2006

Also, patients may also taper their medication if they are considering pregnancy, says Lofton, who notes that its generally recommended to discontinue a GLP-1 agonist two months prior to a planned pregnancy

These challenges led to widespread shortages across nearly the entire class of GLP-1 medications