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If youre not seeing meaningful results after two or three months on the highest dose, your doctor may recommend exploring other options
In patients with T2DM, where islet neogenesis and -cell replication are normal, increased apoptosis is the main cause of the decrease in their -cell numbers, so preventing -cell apoptosis may become an effective means of treating T2DM ( GLP-1 has a beneficial effect on -cell function by promoting -cell proliferation and neogenesis and reducing apoptosis (Zheng et al., 2022)
inhibition of reactive oxygen species-producing enzymes such as xanthine oxidase (XO) and nicotinamide adenine dinucleotide phosphate oxidase (NOX)
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