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The GLP-1s mimic the bodys hormonal pathways, amplifying signals the body already uses to communicate things like hunger and fullness
Glucagon & Energy Expenditure Glucagon receptor activation: Evaluated for effects on hepatic glucose output, lipid handling, and energy expenditure in animal models
However, cotadutide demonstrated superior performance in decreasing liver triglyceride levels and ameliorating mitochondrial functional markers in the liver compared to liraglutide, despite comparable reductions in body weight and food intake between the two treatments [43]
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