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For example, miR-634 can directly repress GRB2, ERK2 and RSK2, hence, inhibition of the Ras-MAPK pathway restores chemosensitivity in ovarian cancer cells [147]
4.4 Cancer associated fibroblasts Cancer-associated fibroblasts (CAFs) are among the most prevalent stromal cells in the breast cancer TME and have a pivotal role in the initiation, development, and resistance of cancer to therapies (119)
This is structurally distinct from GHK alone, which lacks the copper ion that defines the GHK-Cu research compound
Psychiatry investigation, 14(2), 226229
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