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Severe vitamin E deficiency has been associated with specific genetic defects affecting the hepatic trafficking of -tocopherol by -tocopherol transfer protein (-TTP) and transport in lipoproteins (apolipoprotein B)

Clinical reports have not identified differences in responses between elderly and younger patients

This is treated as an absolute contraindication across virtually every published research-community source

While BPC-157 has shown some interesting results in laboratory rodent studies for tendon and soft tissue healing, there are zero peer-reviewed, long-term clinical trials on its safety or efficacy in dogs, she says