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As a major contributor to global mortality and disability, NDDs are associated with diverse pathological mechanisms, including neuroinflammation, oxidative stress, mitochondrial dysfunction, synaptic impairment, and neuronal loss (Lv et al., 2025)
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This review is not comprehensive as we only focused on a subset of the immune cells known to modify ASCVD and were only able to broadly cover ROS modification of signaling as it likely pertains to G6PD-d
Marx N, Federici M, Schutt K, Muller-Wieland D, Ajjan RA, Antunes MJ, et al
Risk of Thyroid C-cell Tumors Inform patients that semaglutide causes thyroid C-cell tumors in rodents and that the human relevance of this finding has not been determined
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