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It is pharmacological certainty
Eur J Pharmacol 589:306314
This mode of action confirms what the experts have been saying for several years, namely that it is a reduction in calorie intake that remains the main means of losing weight (physical exercise has enormous health benefits, but does not have major effects on weight loss)
Inclusion criteria included: (1) patients older than 18 years diagnosed with advanced CRC (stage III or IV), (2) patients with complete clinical data available in the treating hospital, and (3) patients treated with FP-based chemotherapy (FOLFOX, FOLFIRI, CAPOX, Capecitabine) as the first line of treatment
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