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Skin: Structure and Functions: melanin-producing cells derived from the neural crest Neural crest The two longitudinal ridges along the primitive streak appearing near the end of gastrulation during development of nervous system (neurulation)
It works through multiple mechanisms: Appetite regulation : Acts on brain centres controlling hunger and satiety, reducing food intake Gastric emptying : Slows the rate at which food leaves the stomach, promoting feelings of fullness Glucose regulation : Enhances insulin secretion and suppresses glucagon release in a glucose-dependent manner Wegovy is administered as a once-weekly subcutaneous injection, with gradual dose escalation over 16 weeks (0.250.51.01.72.4 mg at 4-weekly intervals) to minimise gastrointestinal side effects
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