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cells express the glucose transporter GLUT2, which facilitates glucose uptake
Epigenetic analysis unveiled hypomethylation of MKRN1 CpG islands, a modification that may drive transcriptional activation
GLP-1R is widely distributed throughout the body, including the pancreas, central nervous system, gastrointestinal tract, cardiovascular system, and adipose tissue ( In our previous studies, we highlighted that abnormal lipid metabolism is closely associated with kidney allograft fibrosis, and we found CPT1A is a critical target in treatment of kidney allograft fibrosis ( To date, research on GLP-1R/GCGR agonists in the treatment of kidney fibrosis remains limited, and the effects of GLP-1R or GCGR agonists on kidney allograft fibrosis have not been investigated
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