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Monitoring: Metabolic: Monitor for signs/symptoms of hypoglycemia GI: Monitor for signs/symptoms of pancreatitis after starting therapy Renal: Monitor renal function in patients with renal dysfunction reporting severe adverse GI reactions (especially when starting or escalating doses) Patient advice: Read the US FDA-approved patient labeling (Medication Guide and Instructions for Use)
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Arachidonic acid (AA) and adrenic acid (AdA) are the main substrates of lipid peroxidation in ferroptosis [19], and the lipid peroxidation process involves three enzymes, namely, acyl-CoA synthetase long-chain family member 4 (ACSL4), lysophosphatidylcholine acyltransferase 3 (LPCAT3), and ALOX
Wu et al., 2024)
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