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3), which is known to upregulate the expression of genes involved in amino acid transport or synthesis, one-carbon metabolism, and glutathione biosynthesis 33,34 (Fig
Immunotherapy and Combination Approaches Although MPNST is generally considered an immune-cold tumor, 2025 trials are combining PD-1 blockade with MEK inhibitors or radiation therapy to enhance immune activation
Estimating intracellular calcium concentrations and buffering without wavelength ratioing
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