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A deeper understanding of IR can be achieved with a more systematic approach involving large-scale omics to study the molecular landscape is of major importance in addition to exploring new intervention strategies to prevent abnormal IR syndrome
Reframing these agents as a central component of cardiovascular risk reduction, separate from their effect on glucose-lowering, places them within each clinicians mandate, yet maintains space for the team of providers to collaborate and focus on each of the key specialty domains for the best health care and outcomes for the patient (Figure 6)
GLP-1 RAs may inhibit retinal neurodegeneration and reduce proinflammatory processes, which could protect against diabetic retinopathy progression
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