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(14) Because all trial data informing this analysis were obtained from relatively short-term trials, we performed a scenario analysis in which the efficacy of each medication on all outcomes decreased by 5% per year from 2020 to 2040

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Ozempic and Rybelsus are indicated for managing blood sugar levels in patients with type 2 diabetes, while Wegovy is FDA-approved for managing body weight in obese and overweight individuals, when used along with healthy habits such as exercise and a balanced diet

Unmapped reads, multiply mapped reads, and PCR duplicates were subsequently filtered out using Sambamba (v0.8.2)