Pola P, Tondi P, Dal Lago A, and et al
Tirzepatide and other incretin-based therapies do not directly interact with thyroid hormone replacement at a pharmacokinetic level

Lupus-specific skin changes include : Localised ACLE - a malar butterfly' rash with redness and swelling over both cheeks, sparing the nasolabial folds, lasting hours to days Generalised ACLE - a diffuse or papular erythema of the face, upper limbs (sparing the knuckles), and trunk resembling a measles-like rash Toxic epidermal necrolysis-like ACLE - associated with lupus nephritis or cerebritis Other mucocutaneous features associated with SLE 30% subacute lupus erythematosus 11% non-scarring alopecia, 7% scarring alopecia 9% discoid lupus erythematosus 6% vasculopathy 5% Raynaud's 4% panniculitis 2% chilblains Other features can include mouth ulcers, urticaria, hypocomplementaemic urticarial vasculitis, non-palpable livedo reticularis, bullous eruptions, oedema of the face and hands, and chelitis Systemic features of SLE Non-erosive arthritis Episcleritis Most patients have renal involvement , and such changes are very important in assessing the prognosis

two-way ANOVA on final body weight with uncorrected Fishers LSD