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Conditions like pernicious anaemia (an autoimmune condition affecting a protein called intrinsic factor vital for B12 absorption), stomach issues (such as from reduced stomach acid or certain medications like proton pump inhibitors), intestinal disorders (like Crohns disease or coeliac disease), or even surgical removal of parts of the small intestine (e.g., gastric bypass surgery) can prevent proper absorption
Persistent pain could indicate another underlying issue or the need to adjust your dosage
2025;doi:10.2337/dci24-0091
For skin anti-aging, tissue repair, and hair support goals, daily dosing is generally preferred for the first 46 weeks of a cycle
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