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Despite the absence of GLP-1Rs on hepatocytes, GLP-1 is involved in hepatic lipid and glucose metabolism, by contributing to fibrosis reversal and liver cells protection in patients with nonalcoholic steatohepatitis (NASH) undergoing GLP-1 RAs (35)
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Understanding these options helps patients make informed decisions about affordability and clinical appropriateness
The combination of both GLP-1 and GIP receptor activation may produce greater anti-inflammatory effects than either hormone alone
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