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The role of GIP in inflammatory responses has been studied by various investigators (Figure 3)
The weight loss from the medication may not benefit pregnant patients and can also cause harm to the fetus
Among the clinical and serological or so called "wet biomarkers" and other non-invasive tools for fibrosis assessment, pro-C3, Fibrosis-4, NAFLD fibrosis score and the enhanced liver fibrosis (ELF) score (an algorithm of hyaluronic acid, amino-terminal propeptide-of-type-III-collagen, tissue-inhibitor of matrix metalloproteinase-1) appear to have promise.[43], [44], [45], [46] Clinical endpoints As discussed earlier, therapies ultimately need to demonstrate efficacy on long-term clinical outcomes
Mechanism of Action GLP-1 agonists exert their effects through multiple mechanisms, all of which contribute to their therapeutic benefits
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