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Officially, even with the committees recommendation, the peptides have not moved out of the regulatory gray area, but will do so if the FDA accepts the committees recommendation

Lip-1 and deferiprone have exhibited consistent neuroprotective effects in preclinical models of glaucoma and DR, while some natural compounds are increasingly recognized for their capacity to modulate the GPX4/Nrf2 axis, thereby suppressing ferroptosis in LECs and Mller cells (75, 125, 126, 128)

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