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These include:[ref] Inflammatory cytokines (IL-1B, IL-33), which cause the release of IL-6, TNF, IL-8, and VEGF Heavy metals (aluminum, cadmium, mercury) Herbicides (atrazine, glyphosate) Pathogens (Lyme disease, lipopolysaccharides from bacteria, certain viruses, and mold spores) These triggers can cause a two-phase reaction : Immediately released mediators include histamine, TNF, tryptase, RANKL, and serotonin
It works by slowing melanin production, which can help fade: Melasma Sun spots Post-inflammatory hyperpigmentation Acne marks Because it changes pigment production, timing matters
K., Wu, Y
Weight change: 1-2 pounds this week (5-6 pounds total from baseline)
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