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The liver also stores nutrients like iron, copper, vitamins B-12, A, D, E and K
Lower SAM in turn leads to reduced production of creatine (the essential backbone for creatine-phosphate) and ubiquinol (CoQ10), the essential electron transfer molecule in the Electron Transport Chain
It will then allow oxygen to circulate through tissues with greater efficiency
Consistent with 85% depletion of hepatic GSH, the KO liver showed much higher basal levels of protein carbonylation (Fig
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