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The SURMOUNT-5 head-to-head trial directly compared tirzepatide to semaglutide and found 47% greater weight loss with tirzepatide at 72 weeks

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Its selective GHS-R1a agonism producing GH release without cortisol or prolactin elevation makes it a valuable tool for investigating the growth hormone axis in isolation from other endocrine effects

Fact: Compounded semaglutide and tirzepatide use the same active ingredients as their branded counterparts