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Oncogene 35 , 57955806 (2016)
Medicinal chemists invested a lot in researching the differences in chemical structure between full agonists, full antagonists and SERM
Electron micrographs were obtained using a transmission electron microscope (Hitachi) at 40,000 magnification
Several other metabolites that were reduced in this studysuch as oxalic, tartaric, pyruvic, and lactic acidhave been reported to influence mitochondrial function by promoting the generation of reactive oxygen species (ROS) and a shift toward anaerobic metabolism
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