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Lifestyle support during maintenance: Nutrition, physical activity, sleep, and stress management become especially important for maintaining results, particularly if the dose is reduced or stopped

Berr, A

As cysts of varying size and number emerge, the kidneys grow larger and their normal structure and function are disrupted

It activates: GLP-1 , just like semaglutide GIP (glucose-dependent insulinotropic polypeptide) , a second hormone involved in appetite, insulin regulation, and fullness Because tirzepatide acts on two hormonal pathways, many patients experience: Stronger appetite control More stable blood sugar Greater total weight loss Better control over cravings Think of tirzepatide as a double-pathway medication that supports weight loss from multiple angles