glp-1 pyy Frontiers JCI - Revisiting leptin's role
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Circulation 142:12051218

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Materials and methods Genetically engineered mouse strains Kras LSL-G12D/+ mice 29 and fElas CreERT mice 30,31 were crossed to generate fElas CreERT ;Kras LSL-G12D/+ double-transgenic mice (called Kras G12D/+ mice after Tamoxifen induction)
Disruption of UPS function is a central pathogenic feature across a broad spectrum of NDDs
