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However, individual outcomes varied
Relationship to expression profiles in other COPD studies In order to show that the gene expression signature of regional emphysema severity is present in larger cohorts of patients with earlier stages of disease, we used GSEA to examine the relationship between genes associated with regional emphysema severity in this dataset and genes associated with COPD phenotypes in other cross-sectional studies [611]
The corresponding fraction was lyophilized, giving 169 mg of the desired product in 41% yield
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