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While evidence suggests GLP-1 receptor agonists have protective effects against arterial disease, the evidence specifically examining venous thrombosis risk is more limited, though no safety signals have emerged

335 Moreover, androgens decrease the type I muscle fibers (TIMF) with highly oxidative and insulin-sensitive properties, while increase type II muscle fibers (TIIMF) that are glycolytic and less insulin-sensitive, further decreasing glycogen synthase expression and favoring the development of IR in PCOS

While weight management is an important aspect of PCOS treatment, the condition can occur independently of a person's body mass index (BMI)

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