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Hair follicles are highly sensitive to environmental and internal stressors

Potential of these effects may be heightened in patients with breast cancer treated with hepatically metabolized chemotherapeutics (e.g., cyclophosphamide, paclitaxel, anthracyclines) or tyrosine kinase inhibitors in which drug-drug interaction-based elevation or lowering of enzyme activity can result in supra-therapeutic drug concentrations, accumulation of toxic metabolites and compromised detoxification of reactive oxygen species facilitating hepatocellular distress

Hes living each day with significant pain, unable to do the thing he loves mostwhich is runand is being told that his only option is surgery

(2022), dgac049