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A full skin examination should be performed to assess for the number and size of caf au lait macules/patches, presence of neurofibromas and axillary freckling

*Correspondence: Parisa Alsadat Dadkhah, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Several mechanistic studies suggest that GLP-1 receptor activation enhances sympathetic activity or reduces vagal tone