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Microbiota-driven ACh dysregulation is validated in inflammatory bowel disease (IBD) models: Dysbiosis-induced choline deficiency is reversed by cytidine diphosphate (CDP)-choline supplementation, which upregulates choline transporter (ChT1), acetylcholinesterase (AChE), and 7 nicotinic acetylcholine receptor (7nAChR) expression to restore neurotransmission (Guo et al., 2023a)
But swallowing the dissolved medication sends it to the stomach, where the peptide faces degradation
Earlier this year, they reported the identification of a series of biomarker signatures that can quantitatively predict which patients are most likely to respond to GLP-1 therapies and sustain that response over time
Asian Pacific Journal of Tropical Disease, 3 (3), 242251
