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How these differ from brand-name Mounjaro Brand-name Mounjaro (manufactured by Eli Lilly) contains only tirzepatide
The article suggests they usually are not
The peptide activates the FAK-paxillin pathway in cells
Steric hindrance from the increased side-chain volume of E14 Cagri and R17 Cagri promotes a shift of the -helix of Cagri away from ECL2 and a slight expansion of the peptide binding pocket at the extracellular side of the CTR TM domain, relative to those observed with rAmy/San385-bound AMYR complexes
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