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Oral glutathione (300 mg daily for four months) led to notable decreases in ALT, suggesting reduced liver inflammation
Chronic studies in rats given 200 mg/kg body weight per day for 104 weeks, dogs given 20 mg/kg PO x 84 days, cats given 40-65 mg/kg for 118 days did not produce any signs of toxicity (blood testing, liver histology)
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3, Oncogenic PI3K/AKT signaling stabilizes and activates nuclear factor erythroid 2related factor 2 (NRF2), a key regulator of antioxidant genes, driving upregulation of GSH biosynthetic enzymes
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