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Adverse events with gastrointestinal symptoms were observed in 37.1%43.6% of patients in the tirzepatide group and 20.4% of patients in the placebo cohort

"This is the first instance where we've seen that semaglutide 2.4 mg enhances cardiovascular outcomes in high-risk patients with a BMI of 27 and above, who have established CVD but do not have diabetes," stated Dr Michael Lincoff, the study's principal author and vice chair for research at Cleveland Clinic's Cardiovascular Medicine Department

As a physician and communicator, I urge us all: no speculation, only compassion and verified information

Tolerability matters