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doi: 10.1111/j.1749-6632.2000.tb06638.x 76 NicolsonG

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With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023

We utilize High-Performance Liquid Chromatography (HPLC) coupled with Mass Spectrometry (MS) to confirm an absolute chemical purity profile of 99% or greater across both active chemical compounds within the matrix