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Conversely, male patients often exhibit normal overall ROS levels in their lymphocytes but show profound, specific mitochondrial lipid oxidative damage

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However, p16INK4a should be combined with additional markers, such as SA--gal (senescence-associated -galactosidase), phosphorylated histone variant H2AX (-H2AX), and SASP factors for accurate identification, as some senescent cells rely on p53/p21/CIP1 pathways instead

Os suplementos alimentares no devem ser utilizados como substituto de uma dieta variada