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Removal or destruction of the stomach: Vitamin B 12 deficiency can develop in people who have had surgery to remove part or all of the stomach
New York, NY: Taylor & Francis
Reduced secretion of gastric acid and pepsin, from the use of H 2 blocker or proton-pump inhibitor (PPI) drugs, can reduce the absorption of protein-bound (dietary) vitamin B 12 , although not of supplemental vitamin B 12
This can lead to a shorter duration of B12 in the body, increasing the need for supplementation or injections to maintain adequate levels
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