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Besides this, the combined therapy of l-carnitine and metformin further significantly decreased the time spent at the periphery of the open field as compared to the untreated diabetic rats and metformin-alone-treated diabetic rats
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Further stratification based on disease progression rate revealed that fast-progressing ALS patients had significantly higher serum ferritin levels than slow-progressing counterparts (335, 340)
23 Interestingly, the current results proved that the treatment with CXRE remarkably augmented the CAT, SOD, and GPx levels while substantially decreasing the LPO level in the RA rats, which supports the hypothesis that CXRE reduces the CFA-induced RA oxidation through its antioxidant property, thereby preventing the further progression of RA condition
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