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7,8 With the rising global prevalence of diabetes driven by aging populations and lifestyle changes, the impact of DN is expected to escalate

Glucagon-like peptide-1 (GLP-1) is a part of a family of peptide hormones known as incretins

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A variant in TCF7L2 , tied to glucose homeostasis and GLP-1 secretion, along with FTO , GLP1R (the receptor these compounds target), and MC4R (central to satiety), maps your baseline metabolic terrain