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While iron chelators have demonstrated efficacy in treating transfusion-associated iron overload in thalassemia patients, their cardiovascular applications remain predominantly experimental (24, 66)
Agents that agonize glucagon-like peptide 1 receptors, including those that co-agonize other anorexigenic hormone receptors, lead to substantial weight loss and benefits in people with varying obesity-related complications, with further trials underway
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