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In adults with BMI 27 kg/m2 and type 2 diabetes, adding tirzepatide to a lifestyle intervention increased weight loss at 72 wk
The UK's MHRA and Australia's TGA have issued formal safety warnings citing melanoma risk specifically
The primary concerns with taking Zepbound early relate to gastrointestinal side effects rather than serious safety issues
For systemic research, certain contraindications exist, such as pregnancy, breastfeeding, active cancer, or conditions like Wilsons disease (a genetic disorder causing copper accumulation)
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