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The CagriSema metabolic preservation mechanism, specifically the maintenance of mitochondrial function in skeletal muscle during weight loss, could theoretically slow the rate of weight regain by preventing some of the metabolic adaptation that makes regain almost inevitable

For individuals with a significant B-12 deficiency, B-12 injections are typically administered weekly until levels normalize

However, WADA-compliant anti-doping testing can detect BPC-157 and related peptides, and the compound is on the prohibited substances list for competitive athletes

Microscopically, transmural hyperemia of the gastrointestinal tract, intestinal mucosa villi reduction, crypt reduction with focal denudation of superficial epithelia, and large bowel dilatation were all inhibited